Goodyer, I. M., Reynolds, S., Barrett, B., Byford, S., Dubicka, B., Hill, J., … & Fonagy, P. (2017). Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial. The Lancet Psychiatry, 4(2), 109-119.

ASPECTS 

The ASPECTS clinical trial looked at how we might support children and young people soon after a traumatic experience like a motor vehicle collision or assault. It was the first trial of its kind in the world. In particular, we looked at whether a psychological therapy called “cognitive therapy” would help children and young people feel better. The study’s main findings are reported in

Meiser‐Stedman, R., Smith, P., McKinnon, A., Dixon, C., Trickey, D., Ehlers, A., … & Dalgleish, T. (2017). Cognitive therapy as an early treatment for post‐traumatic stress disorder in children and adolescents: A randomized controlled trial addressing preliminary efficacy and mechanisms of action. Journal of Child Psychology and Psychiatry, 58(5), 623-633.

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The Health economics findings are here:

Shearer, J., Papanikolaou, N., Meiser-Stedman, R., McKinnon, A., Dalgleish, T., Smith, P., Dixon, C., & Byford, S. (2018). Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model. Journal of Child Psychology and Psychiatry. 59, 773-780 doi:10.1111/jcpp.12851. PDF

PROSPECTS

PROSPECTS was a clinical case series investigating and extended and modified version of CBT-3M for the treatment of PTSD in children who have experienced multiple, repeated traumatic stressors, such as abuse or domestic/community violence. The case series preced the DECRYPT RCT reported above.

Publications;

Smith C, Ford CEL, Dalgleish T, et al. Cognitive therapy for PTSD following multiple-trauma exposure in children and adolescents: a case series. Behavioural and Cognitive Psychotherapy. 2025;53(1):47-62. doi:10.1017/S1352465824000444

MEST

We explored the impact of Memory Specificity Training (MEST) on depressive symptoms. Those who experience depression often find it difficult to recall specific, detailed personal memories, and that this can be related to both current symptoms and experiencing symptoms in the future. This study compared group-format memory specificity training to support using education and discussion to determine how each of these group therapies impact depressive symptoms.

Publications;

Werner-Seidler, A., Hitchcock, C., Bevan, A., McKinnon, A., Gillard, J., Dahm, T., Chadwick, I., Panesar, I., Breakwell, L., Mueller, V., Rodrigues, E., Rees, C., Gormley, S., Schweizer, S., Watson, P., Raes, F., Jobson, L. & Dalgleish, T. (2018) A cluster randomized controlled platform trial comparing group MEmory specificity training (MEST) to group psychoeducation and supportive counselling (PSC) in the treatment of recurrent depression. Behavior Research and Therapy. doi 10.1016/j.brat.2018.03.004

Dalgleish. T., Bevan. A., McKinnon. A., Breakwell. L., Mueller. V., Chadwick. I., Schweizer. S., Hitchcock, C., Watson. P., Raes. F., Jobson. L. & Werner-Seidler. A.. (2014). A comparison of MEmory Specificity Training (MEST) to education and support (ES) in the treatment of recurrent depression: study protocol for a cluster randomised controlled trial. BMC Trials, 15, Article 293.

Neshat-Doost, H.T., Dalgleish, T., Yule, W., Kalantari, M., Ahmadi, S.J., Dyregov, A., & Jobson, L. (2013). Enhancing autobiographical memory specificity through cognitive training: An intervention for depression translated from basic science. Clinical Psychological Science, 1, 84-92.