The Memory Flexibility (MemFlex) intervention for depression

In a series of randomised controlled trials, we have explored the efficacy of Memory Flexibility Training – MemFlex – for clinical depression.

The first trial showed promising efficacy relative to an active counselling control. Free access to the paper at

We then ran a subsequent trial which showed that MemFlex did not decrease the risk of depressive relapse any more than psychoeducation. Free access to the paper at

Together, these studies suggest that MemFlex may help to treat depression, but it doesn’t appear to be any more effective at reducing relapse than our current intervention options. 

You can find out more about the MemFlex intervention on our Resources page. 

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